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The fatty acid modification Tirzepatide C20 fatty diacid modification at position 20 is critical for its extended half-life

Its concentration decreases significantly with age, from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60

Whilst B12 plays an essential role in energy metabolism, red blood cell production, and nervous system function, there is no evidence that supplementation increases energy in individuals with normal B12 status

10.3177/jnsv.61.182 35 YotoA.MuraoS.MotokiM.YokoyamaY.HorieN.TakeshimaK.et al (2012)

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