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Intestinal dysbiosis is common in systemic sclerosis and associated with gastrointestinal and extraintestinal features of disease

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doi: 10.1016/S1081-1206(10)60240-2

The epigenome drifts significantly with age, silencing genes associated with repair and activating genes associated with inflammation and dysfunction

Genetic variants in the NPY gene predict resilience versus vulnerability to mood disorders, further establishing NPY as a fundamental component of emotional regulation

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