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E6 protein can create a ternary complex with p53 and ubiquitin ligase (E6AP), causing to the ubiquitination and proteasomal degradation of p53 [105]

Peer review Peer review information Nature Reviews Urology thanks Angele Boursier, Ranjith Ramasamy and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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4.4.4 GPX and hemibiotrophic pathogens-specific responses Hemibiotrophic pathogens, which alternate between biotrophic and necrotrophic phases during infection, present unique challenges in plant defense (Glazebrook, 2005)

These peptides, which are usually short, can cross the cell membrane due to their amphipathic structure (one hydrophobic and one hydrophilic part), which helps them interact with membrane lipids

Effectiveness Monitoring: Alert healthcare provider of any unexpected changes or if common side effects persist