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Nature Biotechnology

Symptoms of folate deficiency Some of the symptoms that can be caused by a lack of folate include: General symptoms Fatigue Irritability Headache Dizziness Gastrointestinal symptoms Sore tongue Mouth ulcers Diarrhea Loss of appetite Neurological symptoms Numbness and tingling in the hands and feet Confusion Depression Cognitive impairment Dementia Hematological symptoms Anemia (pale skin, shortness of breath) Testing for vitamin B12 and folate deficiency When to test Since vitamin B12 and folate affect many functions in the body and there are many possible symptoms, blood testing for vitamin B12 and folate is commonly ordered by the physicians at the Adult Down Syndrome Center

Tesofensine side effects can include dry mouth, difficulty sleeping, anxious feelings, increased blood pressure, and serotonin syndrome (if combined with antidepressant medication.) Who should NOT use Tesofensine

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Only a few cases due to vitamin B12 have been reported in the literature

Vitamin B12 has been proposed as a perspective aid in the management of weight