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This metabolic transformation also results in reduced affinity of the compound for its cellular target

First, Daszynski et al (160) found that 0.2 mM lanosterol and 0.25 mM or 0.5 mM 25-hydroxycholesterol did not raise the soluble lens protein levels and restore cataract lens clarity

To the supernatant [1.0 M], 1.0 mL KI and 0.5 mL K 3 PO 4 buffer (10 mM, pH 7.0) were added

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It is a naturally occurring compound in the body and taking it as a supplement simply boosts its levels