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Routine housing, husbandry and exercise regimens were maintained throughout the course of each study

Intracellular cystine depletion by aminothiols in vitro and in vivo

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J.McGreadyR.JullienV.TarningJ.LindegardhN.PhyoA

Epithelial MLCK-dependent barrier dysfunction mediates T-cell activation-induced diarrhea in vivo Cytoskeletal contraction due to myosin II (regulatory)-light chain (MLC) phosphorylation is necessary for barrier disruption and in vitro inhibition of myosin light chain kinase (MLCK) restores barrier function following cytokine treatment