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Certain health conditions that affect the gut, like Crohns or celiac disease, can also make absorption a major challenge
Being proactive about testing isn't just a good idea
Niacin can also have an antagonistic effect on gout medications: it elevates uric acid levels, which may counteract drugs like allopurinol or pegloticase that are meant to lower uric acid
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However, despite the widespread nature of this condition, there are no internationally standardised guidelines regarding dosage regimes, optimal formulation, frequency of administration of B12 therapy and monitoring of therapeutic effect, leading to significantly variable international practice ( In this review, we aim to summarise the complex pathway by which B12 is absorbed and metabolised and subsequently describe the inherited and acquired causes of B12 deficiency
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