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To test the involvement of NRF2, we bred the Gclc f/f mouse strain with the Nrf2 f/f mouse strain 57,58 and induced a liver-specific double deletion with the AAV-TBG-Cre virus (hereafter referred to as L-DKO) (Fig

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and (iii) analyzing gene expression patterns in adipose tissue, liver, and other relevant organs to identify their target genes in the context of obesity

Uysal N, Kizildag S, Yuce Z, Guvendi G, Kandis S, Koc B, et al

In the current study, we have applied a refined version of the workflow to specifically predict both, common essential genes across various cancer types, and melanoma-specific essential genes that could potentially be used as drug targets for melanoma treatment

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