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Caspase-3 (cysteinyl aspartate-specific proteinase-3) is an important proteolytic enzyme responsible for the execution of apoptosis

PMID: 30609670

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TLR9 activation can mediate NF-B phosphorylation through myeloid differentiation factor 88 (MyD88) and then translate various factors, including IL-1, IL-6, and TNF-, to mediate the inflammatory cascade (172)

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For example, impaired GSH metabolism contributes to PD pathogenesis