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Additionally, chronic oxidative stress can lead to a depletion of cellular glutathione levels

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10.1016/j.mri.2019.10.004 Summary Keywords magnetic resonance spectroscopy, glutathione, metalloproteinase (MMP), myeloperoxidase (MPO), psychiatric disorder, posttraumatic stress disorder (PTSD) Citation Watling SE, Rhind SG, Warsh J, Green D, McCluskey T, Tong J, Truong P, Chavez S, Richardson JD, Kish SJ and Boileau I (2023) Exploring brain glutathione and peripheral blood markers in posttraumatic stress disorder: a combined [1H]MRS and peripheral blood study

The resulting inflammation creates a painful cycle where swelling leads to more impingement which causes more swelling

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