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Comparison and Clinical Implications Final Verdict: Platelet-Rich Plasma is a Validated Treatment, While Peptide Therapy Requires Further Research While peptide injections show promise in preclinical studies, their role in musculoskeletal treatment remains experimental , with a lack of well-controlled human trials to confirm their efficacy

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Isotretinoin has been associated with altered platelet function in case series, and EPA in particular inhibits thromboxane A2-mediated platelet aggregation [6]

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