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101 Data on the NAC effects in COPD suggest that NAC reduces elastase activity, 99 hinders the loss of pulmonary glutathione, abolishes the effects of cigarette smoke, prevents thickening of the airway wall, and reduces the risk of exacerbations

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Discussion In this work, we have used constraint-based metabolic modeling to investigate the metabolic state of virally infected cells and identify potential targets for broad-spectrum antiviral treatment