addictive ingredients in cigarettes Most tobacco products, including e-cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other products, using a nicotine product builds tolerance, leading to more FDA Tobacco Education & Prevention

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Importantly, microfractures occurred in response to aerosols containing only propylene glycol and vegetable glycerol, suggesting this effect was not entirely mediated by nicotine or flavouring chemicals [37]

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