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Potential Health Risks: The long-term health effects of these nicotine analogs, especially when heated and inhaled, are not well understood, highlighting the need for further research and regulatory scrutiny

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However, this increased risk was observed among adolescents who had no prior intention to smoke, but not among those who had previously expressed an intention to smoke 86

Benzo[a]pyrene binds to the p53 gene segment of DNA, causing a mutation in the p53 gene that leads to lung cancer