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108 Additionally, chromosomal instability, which is a hallmark of cancer, 109 is responsible for driving somatic copy number variations and intratumor heterogeneity within subclones during cancer progressions

Medicine 99 , e22152 (2020)

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However, a small number of GHR antagonists are in clinical trials or preclinical development, and we anticipate that these will eventually expand the options available for clinical and research applications

Phytochemicals from fruits, vegetables, spices, teas, and herbs demonstrate therapeutic efficacy in preclinical TBI models through their anti-inflammatory, antioxidant, and anti-apoptotic properties