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Such a unique system may allow c-MET to respond differently at low or high HGF concentrations

PGPIN I, II and III groups were respectively gavaged PGPIN at 0.025mg, 0.25mg and 2.5mg/kg body weight each day before alcohol gavage, and GSH group was gavaged GSH at 2.5mg/kg body weight as positive control

Multiple factors can deplete glutathione levels, including: Aging: Glutathione levels naturally decline with age

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In a relatively recent review by Al-Samerria and Radovick [9], the role of IGF-1 in the regulation of the GH-axis was addressed

Cell viability assays The cells were plated in triplicate in 96-well plates (4000 cells cultured in 2%FBS DMEM and 2000 cells cultured in 10% FBS DMEM)