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The papillary dermis is where fibroblasts respond to mechanical injury by triggering the wound-healing cascade and to GHK-Cu, PDRN, and growth factors by initiating collagen synthesis [2]

Whether these materialize depends on funding and regulatory willingness to allow investigational use

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More VEGF means more vascularization, which means better delivery of nutrients and immune cells to the injury site

Yet, a static description cannot capture function

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