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Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children

If an individual lacks a functional liver enzyme called FMO3, they cannot degrade TMA into a non-smelly chemical form, trimethylamine oxide, or TMAO

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Discovery-based approaches focus on identifying changes in relative abundances of new or novel molecular species that are statistically significantly associated with a disease or toxicity state