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GSTs play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione

high SAH may inhibit DNA methyltransferases (DNMTs), thus reducing methylation and causing possible uncontrolled gene expression (205)

iberna, L., Jenko-Pranikar, Z., & Petelin, A

10.3390/cancers13174375 183 ShuklaK.FerrarisD

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293,294 YAP can inhibit glucose-6-phosphatase catalytic subunit (G6PC) and phosphoenolpyruvate carboxykinase 1 (PCK1) via peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1), eventually hampering gluconeogenesis