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Understanding its effects enables you to navigate treatment confidently

While inhibitor kappa B kinase 2 (IKK2) in joint mesenchymal cells is necessary for cartilage destruction and bone erosion, in its absence synovitis still develops, as a result of local immunogenic synovial fibroblasts necroptosis

Excess inflammation can cause swelling and protect the area too long

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[PMID:34606698] Takeoka Y, Matsumoto K, Taniguchi D, et al