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McGill B, Rose S, Watts C, Egger S, Brooks A, Jenkinson E, West R, Dessaix A, Madigan C, Freeman B
Data collection This study was carried out during the peak of the second wave of the COVID-19 pandemic
Analyzing the effects on gene expression and DNA methylation that are shared between smoking and aging, the researchers noted that in people who quit smoking, non-reversible DNA methylation sites in the lung were enriched in DNA methylation sites that are associated with aging signatures, but this wasnt the case for reversible and partially reversible sites suggesting that the smoking effects that affect DNA methylation in common to aging are more persistent in time. This was not the case for gene expression changes
l Nasal cavity and paranasal sinus cancers occur behind the nose
Learn more about the effect of cigarette use