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Firstly, it decreases the biosynthesis of essential vitamins like thiamine and folic acid, which may contribute to observed vitamin deficiencies [154,155,156]

Genetic Polymorphism of the Human Cytochrome P450 2C9 Gene and Its Clinical Significance

J Biol Chem 278:4686946877 Conklin PL, Foyer CH, Hancock RD, Ishikawa T, Smirnoff N (2024) Ascorbate acid metabolism and functions

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