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Half Life. (2020)

Biochemically, rats exposed to nicotine (2.5 mL/kg) showed a significant increase of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) in serum due to hepatocyte cell death/damage

In this paper, the Tobacco Leaf Disease Detection Dataset was utilized, which has high-resolution tobacco leaf images classified based on disease classes, covering a range of conditions from tobacco curing

Normal condition

From 2021 in Milan smoking was prohibited in gardens, children play areas, public bus stops and in sporting localities

That has changed to some degree but there are still concerns that these products are used primarily for things other than tobacco