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Alternative therapies in health and medicine, 30 (10), 1217

R The conjugation itself is catalyzed by glycine N-acyltransferase (GLYAT) in the mitochondrial matrix (for glycine) or by ACNAT enzymes for other amino acids

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Lung, WAT, testis, and skeletal muscle preferentially rely on salvage and have low expression of proteins involved in the PreissHandler pathway 41 , with the muscle in particular relying on both NRK1 and NRK2 for supporting its mitochondrial metabolism and fiber type composition 42

Ideally these IVs should be continued for 3-6 months for optimal results.

doi: 10.1038/s41564-024-01795-7 489 ZhouZ.ShytiI.KimJ.YouL