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METHODS Sample Participants in the ITC4 Survey were 9058 adult smokers (18 years or older, smoked more than 100 cigarettes in their life, and smoked at least once in the past 30 days) in four countries: CAN (n = 2114), USA (n = 2138), UK (n = 2401), and AUS (n = 2305)

Accordingly, this estimate should be interpreted as an imprecise one

Acknowledgements We thank Dr Kyoji Okita for insightful comments and for his role in the preparation of the graphs contained in this manuscript

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The second, ganja, consisting of the leaves and the plant tops, is smoked

The effect of smoking can be devastating in the long run