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Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

The activation of the NLRP3 inflammasome mediates the cleavage of caspase-1 and the secretion of the IL-1 proinflammatory cytokine, ultimately inducing cell death through a process known as pyroptosis

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doi:10.1007/s12015-020-09969-6

Ecology 54:427432

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