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STAT3 dimers subsequently move to the nucleus and modulate cyclin D1 expression, influencing the G1/S transition in hepatocytes

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GSTM could not enter the nucleus of RAW264.7 cells under LPS stimulation, further confirming the importance of Ser184 phosphorylation for GSTP to enter the nucleus

coli , and lowers infection risks and disease severity (156)

Under conditions of severe oxidative or genotoxic stress, p53 promotes transcription of pro-apoptotic genes such as Bax and PUMA, thereby facilitating mitochondrial outer membrane permeabilization and apoptosis (48, 49)

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