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However, hepatocytes do not strictly depend from ME-1 activity for NADPH synthesis: in ME-1 deficient mice, after an initial depletion, the GSH levels recover quickly and sensitivity to acetaminophen-induced liver injury was unaltered [26]

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Cell 90:523535 Singh A, Soler JA, Lauer J, Grill SW, Jahnel M, Zerial M, Thutupalli S (2023) Two-component molecular motor driven by a GTPase cycle

Pillai S, Oresajo C, Hayward J