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The inability to properly utilize L-carnitine and fatty acids creates a vicious, self-perpetuating cycle of oxidative stress and systemic inflammation that wreaks havoc across multiple organ systems

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PLoS ONE 8:e69415

In the companys supplemental NDA, Neurocrine included data from the Phase III KINECT-HD trial and the ongoing KINECT-HD2 open-label study to establish the safety and efficacy of Ingrezza in the proposed indication

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