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The phenotypic and functional interrelationships of these three subsets within the tumour micro-environment (TME) remain to be fully elucidated

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Pure MSN, Cu doped MSN (Cu-MSN) and Zn doped MSN (Zn-MSN) were also synthesized as control groups by the same procedure using the corresponding ingredients with the same amounts

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Importantly, functional analysis showed the transcriptome included nearly all enzymes for key metabolic pathways, specifically 21 of 22 enzymes involved in aromatic amino acid synthesis and all eight enzymes required for branched-chain amino acid ( Later, transcriptomic studies in A

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