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Other SUMO-deconjugating enzymes such as human sentrin-specific proteases, i.e., SENP3 and SENP5, were reported to localize to the mitochondria, playing a role on mitochondrial fission and mitophagy 87,88
Another protein with extensive connections is sequestosome-1 (SQSTM1), which interacts with 18 proteins, might play a critical role in apoptosis process
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[DOI] [PubMed] [Google Scholar] de Keizer PL, Burgering BM, Dansen TB
Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing
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