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Mechanisms of Bilirubin Neurotoxicity Spectrum of Effects of Bilirubin on Cellular Functions The mechanism of injury of neurons by bilirubin is not entirely resolved, but recent work has provided important insights (see later)

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Although it is generally recognized that serum levels of unconjugated bilirubin must be elevated to cause neurotoxicity, the relationship between such elevations and brain injury is not simple

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10.1001/jamapsychiatry.2013.4374 129 ErnyD.Hrab De AngelisA