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Oral B12 supplements have to pass through the gut, and absorption can be limited especially if you have digestive issues, take certain medications like metformin or antacids, or simply have low stomach acid

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Symptoms of vitamin B12 deficiency Symptoms of vitamin B12 deficiency or folate deficiency anaemia Deficiency is more common than most people think, particularly in those who follow a vegetarian or vegan diet, as vitamin B12 is primarily found in animal products