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Macrophages are highly heterogeneous, with diverse phenotypes, although their heterogeneity in the context of e-cigarette vaping has not been addressed in depth, and the human data we do have is conflicting

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Case-controlled studies and cohort studies have not shown an increased risk [54, 55], while other epidemiological studies have reported associations with lung cancer with heavier marijuana use

Cigarette smoke is also an eye irritant and can lead to a breakdown in tear film when it hits the eye, leading the eye to dry out and leaving it red and uncomfortable