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10.2174/092986712803414015 79 SikiricP.SeiwerthS.RucmanR.TurkovicB.RokotovD

23 Supplementation of 1 mg daily is recommended for patients with specific risk factors (e.g., bariatric/gastric surgery patients, those with severe malnutrition, chronic alcohol use, chronic hemolytic anemia and conditions with high cell turnover, and use of antimetabolite medications such as methotrexate)

The proposed mechanisms include upregulation of growth hormone receptors in fibroblasts, modulation of the nitric oxide (NO) system for enhanced angiogenesis (new blood vessel growth), and reduction of inflammatory cytokines

These symptoms should improve with continued use, not worsen indefinitely

At the low research doses described in the literature, no serious adverse events have been systematically documented

the genuinely mixed VitaMIND and Finnish Vitamin D supplementation trials