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In some embodiments, a formulation or composition disclosed herein is then deposited on or near the round window or crista fenestrae cochleae for localized treatment

Zonula occludens-1 (ZO-1, batch number AF5145), Beta-Actin antibody (batch number AF7018), Goat Anti-Mouse IgG (H + L) HRP (batch number S0002), and Goat Anti-Rabbit IgG (H + L) HRP (batch number S0001) were obtained from Affinity

Replication studies should integrate a positive control (e.g., memantine, donepezil) to validate the paradigm

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