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FOXO4-DRI promotes apoptosis in senescent cells As established in prior research, FOXO4-DRI competitively binds to p53 with high affinity, thereby disrupting its nuclear interaction with FOXO4

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24 24 24 The exact mechanism by which chromium influences CRP levels is not precisely known, but it is suggested that its inhibitory effect on pro-inflammatory cytokines is related to the reduction of oxidative stress, which decreases CRP 24 24 25 SELENIUM It is an essential trace element with antioxidant properties, fundamental for selenoproteins that regulate the function of endothelial cells and protect against oxidative damage