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A deficiency may lead to a wide range of symptoms, including: Ongoing fatigue or low energy Brain fog or difficulty concentrating Low mood or irritability Pale skin or a yellow tinge Tingling or numbness in the hands and feet Shortness of breath Dizziness or feeling faint Mouth ulcers or sore tongue Blurred vision Some of these symptoms may also be caused by iron deficiency

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In aged mice, researchers observed improvements in physical function, fur density, kidney function, and other markers after FOXO4-DRI treatment

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