Therefore, it would seem advisable to perform a sleep study (e.g., PSG) before initiating GH therapy in children with GHD
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This can lead to increased intracranial pressure (ICP), which can affect the respiratory and neurologic systems, as well as the childs development
How the dose of drug may need to be altered to prevent toxicity in some cases of liver or renal impairment
[DOI] [PMC free article] [PubMed] [Google Scholar] Whitworth AJ, Theodore DA, Greene JC, Benes H, Wes PD, Pallanck LJ
The Journal of general physiology.139(6)