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This reduced binding means that a much higher proportion of gave IGF1 LR3 remains free in solution and available for receptor interaction
Acknowledgements The authors are grateful for the support received from the Austrian Science Fund (FWF, P 29379-B28), the Tyrolean Science Fund (TWF, 0404/1812), the Austrian Society of Gastroenterology and Hepatology (GGH) and the European Crohns and Colitis Organisation (ECCO) (to T.E.A.)
At physiological pH, the carboxylic (COOH) group of glucuronic acid becomes ionised
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