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If fatigue is ongoing, unexplained, or affecting your quality of life, it may be worth exploring whether B12 deficiency is a contributing factor

CAPS-5 scores range from 0 to 80

Immune complexes inhibit IL-1 secretion and inflammasome activation

B12 deficiency can also cause water retention, constipation, muscle weakness, fatigue, and weight loss

It should be noted that changes in acne due to any pharmaceutical treatment or dietary changes are likely to take at least 10 to 12 weeks, so you have to stick with it

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