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Addition of 3,000 nM of the representative dimer macrocycle, aML5-PEG3, did not prevent EGF-induced phosphorylation of EGFR (Supplementary Fig

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They measured the full B12 body count of four people and found it to be 780 to 1,350 g of B12 with a daily loss of 0.12% for a maximum loss of 1.6 g per day or 11.2 g per week

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Timing of administration may influence interaction dynamics