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Conclusion GLP-1 medications like semaglutide and liraglutide have transformed the way diabetes and weight loss are managed, but newer drugs like Mounjaro (tirzepatide) offer even more benefits through their dual action on both GLP-1 and GIP receptors

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We then summarise the disparate practice in B12 replacement internationally and highlight the more novel methods of B12 administration, including subcutaneous, intra-nasal and sublingual modes in comparison to intramuscular and oral routes

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[ref] Related article: NOS3 gene and nitric oxide Gut-brain axis: Nerves running from the brain to the intestines can move neurotransmitters and send signals in both directions

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