Rather than binding to a single receptor like most drugs, this peptide influences numerous biological pathways simultaneously
When NNMT is overactive, less nicotinamide is available for recycling, and cellular NAD+ levels fall
The initial findings were so impressive that some researchers suggested BPC-157 could be the prototype of a new class of organoprotective agents. There were still many unanswered questions, though: Would other studies replicate these findings
Although BPC 157 has shown promising results in preclinical studies, further research and clinical trials need to be done in order to determine its potential therapeutic application and safety in humans
it cannot make a high dose appropriate for a low-substrate body, remove the heart-rate tail in a sensitive person, or guarantee anyone reaches 15 mg in real life
Pang, Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts, Mol