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The blood-labyrinth-barrier (BLB), which includes a blood-endolymph barrier and a blood-perilymph barrier, consists of tight junctions between specialized epithelial cells in the labyrinth spaces (i.e., the vestibular and cochlear spaces)

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Alpha-Arbutin: Targets uneven skin tone and helps fade hyperpigmentation

Curcumin targets cell wall integrity via calcineurin-mediated signaling in Candida albicans

In contrast, ATF4 mainly drives CHAC1 transcription under stress conditions through its interaction with both the ATF/CRE and ACM motif (Nomura et al., 2020)

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