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Treatment began when tumors reached ~100 mm, with mice randomized to vehicle, APR-017(100 mg/kg per day, ip

[DOI] [PMC free article] [PubMed] [Google Scholar] 112.Molhoek K.R., Erdag G., Rasamy J.K., Murphyg C., Deacon D., Patterson J.W., Slingluff C.L., Jr., Brautigan D.L

and 2) the formation of fibrotic tissue after cardiac insult resulting in ventricle remodeling and decreased compliance

(2013) Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

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Cardiovascular Protection Studies Research reveals comprehensive cardiac protection including prevention of heart failure, normalization of elevated endothelin levels, and reduced long-term effects following myocardial infarction