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Data obtained by the AVANT trial of adjuvant bevacizumab in colorectal cancer shows evidence of higher incidence of relapses and deaths in bevacizumab treated patients due to disease progression suggesting an increased tumor aggressiveness after anti-angiogenic therapy [288]

In animal models, BPC-157 has been studied most extensively for tendon healing, GI mucosal repair, bone repair, and neuroprotection

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The expression of Wnt pathway inhibitors Sfrp4 , Sfrp5 , and Dkk1 was significantly decreased in the anwuligan 2 mg/kg group (Supplementary Materials)

PLoS ONE 12:e0187964

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