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Methods Plasmids and lentivirus construction To tag the catalytic subunit of human GCL with a mitochondrial-targeting epitope, the 5-end of the full-length (2,023 bp) cDNA-encoding GCL (GenBank accession number NM_012815) was fused with a cDNA fragment encoding the first 32 amino acids of human ornithine transcarbamylase (GenBank accession number NM_000531)

Electronic supplementary material ESM 1 (download DOCX (DOCX 381 kb) Rights and permissions About this article Cite this article Jalili, R., Khataee, A

DAMPs then activate nuclear factor kappa-B (NF-B) via the advanced glycation end product (AGER) pathway, leading to an immune response [28]

Rizk AA, Shawky YM, Motawie AG

113 LiangG.YangJ.HortonJ

Glycemic control: In type 2 diabetes patients, HbA1c dropped by 1.32.0% (from ~8.0% to ~6.0%) with 412 mg doses [1]