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Melanotan II, by contrast, is a cyclic heptapeptide engineered to be more potent but less selective

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10.1016/j.mam.2009.01.001 Mol Asp Med

Additionally, with the combined action of IR and excessive androgen in PCOS patients, TF inhibition is decreased, iron absorption in the intestine is increased, and iron release from macrophages is decreased, leading to iron overload (143)