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We anticipated the potentially sensitive population of variants to represent a small fraction of the total MITE variant population, resulting in little to no observable shift in the overall variant representation distribution (Fig

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Thus, the interactions of FcRn with IgG and albumin are distinct, and the two ligands bind the receptor non-competitively and simultaneously to effectively form a ternary IgG:FcRn:albumin complex [26, 72]

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